SCHEMBL5846204

SCHEMBL5846204

Cc1cc(C)cc(CCC(=O)O)c1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 11/20 0.61
▸ FFAR4 Q5NUL3 3/20 0.57
▸ NPSR1 Q6W5P4 1/20 0.54
▸ KEAP1 Q14145 1/20 0.52
▸ THRA P10827 2/20 0.49
▸ THRB P10828 2/20 0.49
▸ GPR17 Q13304 1/20 0.46
▸ TPMT P51580 1/20 0.44
▸ RXRA P19793 1/20 0.43
▸ RXRB P28702 1/20 0.43
▸ RXRG P48443 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14143792 0.88 FFAR1 (0.50) FFAR1FFAR4NPSR1KEAP1THRA
SCHEMBL22190396 0.87 MAPK1 (0.55) FFAR1FFAR4NPSR1RXRARXRB
SCHEMBL22088079 0.86 FFAR1 (0.49) FFAR1FFAR4NPSR1KEAP1THRA
SCHEMBL17705230 0.86 THRA (0.50) FFAR1FFAR4NPSR1KEAP1THRA
SCHEMBL12834744 0.86 FFAR1 (0.49) FFAR1FFAR4NPSR1KEAP1THRA
SCHEMBL28045328 0.85 MAPT (0.55) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL28030638 0.84 KMT2A (0.46) FFAR1FFAR4NPSR1TPMT
SCHEMBL23599377 0.83 FFAR1 (0.50) FFAR1FFAR4THRATHRB
SCHEMBL5670212 0.83 KEAP1 (0.64) FFAR1FFAR4NPSR1KEAP1THRA
SCHEMBL9632300 0.82 ALDH1A1 (0.54) FFAR1FFAR4THRATHRBTPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102307860-A GPR120 receptor agonists and uses thereof METABOLEX INC 2012-01-04 — — CN claimed
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2025-05-29 — — US disclosed
EP-4469803-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2024-12-04 — — EP disclosed
WO-2023144240-A1 GLUCOSE SENSITIVE INSULIN DERIVATIVES AND USES THEREOF NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) 2023-08-03 — — WO disclosed
WO-2023144545-A1 SACCHARIDE SENSING SYSTEMS Carbometrics Limited (GB) 2023-08-03 — — WO disclosed
CN-113321640-B Indole compound and application thereof 中国科学院广州生物医药与健康研究院 2023-06-09 — — CN disclosed
CN-109111427-B Indole compound and application thereof 中国科学院广州生物医药与健康研究院 2023-06-02 — — CN disclosed
WO-2020139636-A1 (PYRIDIN-2-YL)AMINE DERIVATIVES AS TGF-BETA R1 (ALK5) INHIBITORS FOR THE TREATMENT OF CANCER NEXYS THERAPEUTICS, INC. (US) 2020-07-02 — — WO disclosed
CN-106414434-A Isothiazole derivatives as gpr120 agonists for the treatment of type ii diabetes 詹森药业有限公司 2017-02-15 — — CN disclosed
CN-105209444-A Benzo-fused heterocyclic derivatives useful as agonists of GPR120 JANSSEN PHARMACEUTICA NV 2015-12-30 — — CN disclosed
CN-102958914-B 1-phenyl substituted heterocyclic derivatives and their use as prostaglandin D2 receptor modulators ACTELION PHARMACEUTICALS LTD 2015-05-27 — — CN disclosed
CN-102307860-A GPR120 receptor agonists and uses thereof METABOLEX INC 2012-01-04 — — CN disclosed
US-7012138-B1 Chiral polysaccharide esters, one of the methods for preparing them and their uses for obtaining optically enriched acids or for chiral chromatography UNIVERSITE DE DROIT D'ECONOMIE ET DES SCIENCES D'AIZ-MARSEILLE (FR) 2006-03-14 — — US disclosed
EP-1135417-B1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY UNIV DROIT D ECONOMIE ET DES S (FR) 2003-06-25 — — EP disclosed
EP-1135417-A1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY Universite De Droit, D'Economie et des Sciences D'Aix-Marseille (FR) 2001-09-26 — — EP disclosed
WO-2000032638-A1 POLYSACCHARIDE CHIRAL ESTERS, ONE OF THE METHODS FOR PREPARING THEM AND THEIR USES FOR OBTAINING OPTICALLY ENRICHED ACIDS OR CHIRAL CHROMATOGRAPHY UNIVERSITE DE DROIT, D'ECONOMIE ET DES SCIENCES D'AIX-MARSEILLE (FR) 2000-06-08 — — WO disclosed
EP-0393668-B1 Method of preparation of benzaldehyde dialkyl acetals and new benzaldehyde dialkyl acetals BASF AG (DE) 1994-02-02 — — EP disclosed
EP-0393668-A2 Method of preparation of benzaldehyde dialkyl acetals and new benzaldehyde dialkyl acetals BASF Aktiengesellschaft (DE) 1990-10-24 — — EP disclosed
US-4544450-A Electrochemical process for the synthesis of organic compounds ANIC S.P.A. (IT) 1985-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250172566-A1 SACCHARIDE SENSING SYSTEMS GALE, SLC2A8, SLC2A4 FFAR1 2248/4885FFAR4 1894/4885NPSR1 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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