Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162882 | 0.87 | NPC1 (0.52) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL29531311 | 0.85 | CYP2D6 (0.38) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL12569555 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL21003972 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL12087087 | 0.79 | ALDH1A1 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2FLT3 | |
| SCHEMBL17785118 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL17969087 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL21865143 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL12626506 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E | |
| SCHEMBL1707058 | 0.79 | CYP2D6 (0.49) | CYP2D6HIF1APOLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209444-A | Benzo-fused heterocyclic derivatives useful as agonists of GPR120 | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |