Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | CTSG | P08311 | 3/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1786954 | 0.92 | DAO (0.48) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784704 | 0.88 | TSHR (0.44) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784532 | 0.84 | TSHR (0.47) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL4577183 | 0.83 | TSHR (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL569274 | 0.83 | TSHR (0.58) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27642058 | 0.81 | TSHR (0.44) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1789329 | 0.81 | DAO (0.47) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL28604331 | 0.80 | TSHR (0.42) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL17595203 | 0.80 | DAO (0.54) | DAOTSHRNAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784796 | 0.79 | DAO (0.45) | DAOTSHRNAPRTPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102453186-B | A kind of preparation method of propylene-ethylene random copolymer | SINOPEC CORP. (CN) | 2016-04-27 | — | — | CN | disclosed |