SCHEMBL28045359

SCHEMBL28045359

c1ccc(CC(SSC(Cc2ccccc2)C2CCCCC2)C2CCCCC2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
EPHX2 P34913 1/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
IDO1 P14902 2/20 0.40
MME P08473 1/20 0.39
ACE P12821 1/20 0.39
CPA1 P15085 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
PKM P14618 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
EPHX1 P07099 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3966885 0.79 EPHX2 (0.44) CYP1A2CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL11868464 0.76 EPHX1 (0.43) TDP1EPHX2IDO1MMEACE
SCHEMBL25518645 0.76 EPHX2 (0.46) TDP1EPHX2SMN1; SMN2MMEACE
SCHEMBL10716724 0.76 DPP4 (0.49) CYP2D6TDP1EPHX2IDO1PKM
SCHEMBL8806240 0.76 SIGMAR1 (0.46) CYP2D6TDP1EPHX2TAAR1SIGMAR1
SCHEMBL3289204 0.76 DPP4 (0.49) CYP2D6TDP1EPHX2IDO1PKM
SCHEMBL31494761 0.76 CYP2D6 (0.52) CYP2D6TDP1EPHX2TAAR1SIGMAR1
SCHEMBL11022079 0.74 IDO1 (0.43) CYP1A2CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL2467478 0.74 MEN1 (0.53) CYP1A2CYP3A4CYP2D6TSHRCYP2C19
SCHEMBL3285405 0.73 EPHX1 (0.50) CYP2D6TDP1IDO1PKMEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103965086-B A kind of method of synthesize benzyl alkyl disulfide PLA 63975 ARMY (CN) 2015-12-30 CN disclosed