SCHEMBL28045406

SCHEMBL28045406

NNP(=O)(O)Oc1ccc(Cl)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
HPGD P15428 1/20 0.46
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
MMP2 P08253 2/20 0.44
CA14 Q9ULX7 2/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP14 P50281 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049339 0.79 CYP1A2 (0.53) LMNAALDH1A1MAPTCYP1A2CYP2C9
SCHEMBL1059938 0.77 MEN1 (0.61) MEN1KMT2AHPGDCA2CA9
SCHEMBL2472085 0.77 MEN1 (0.61) MEN1KMT2AHPGDCA2CA9
SCHEMBL10622036 0.76 MEN1 (0.55) MEN1KMT2AHPGDCA2CA9
Water SCHEMBL29937078 0.75 MEN1 (0.59) MEN1KMT2AHPGDCA2CA9
SCHEMBL10622033 0.75 MEN1 (0.59) MEN1KMT2AHPGDCA2CA9
Hydrochloric Acid SCHEMBL27651690 0.75 MEN1 (0.59) MEN1KMT2AHPGDCA2CA9
SCHEMBL28200119 0.75 CA2 (0.67) MEN1KMT2ACA2CA9MMP2
SCHEMBL28401375 0.74 MEN1 (0.44) MEN1KMT2AHPGDCA2CA9
Methyl Alcohol SCHEMBL29937073 0.74 MEN1 (0.57) MEN1KMT2AHPGDCA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107663160-B A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt 上海惠和化德生物科技有限公司 2019-03-01 CN claimed
CN-105272875-A 4-chlorophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN claimed
CN-107663160-B A kind of continuous flow synthesis technology of 4- chlorobenzene hydrazonium salt 上海惠和化德生物科技有限公司 2019-03-01 CN disclosed
CN-107663160-A A kind of continuous stream synthesis technique of 4 chlorobenzene hydrazonium salt 上海惠和化德生物科技有限公司 2018-02-06 CN disclosed
CN-105272875-A 4-chlorophenylhydrazine phosphate preparation method TIANJIN CHEM REAGENT RES INST 2016-01-27 CN disclosed