Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.41 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24491967 | 0.88 | DPP4 (0.60) | DPP4HPGDRECQLEPHX1NR1H2 | |
| SCHEMBL1168519 | 0.88 | DPP4 (0.60) | DPP4HPGDRECQLEPHX1NR1H2 | |
| SCHEMBL2222675 | 0.88 | DPP4 (0.60) | DPP4HPGDRECQLEPHX1NR1H2 | |
| SCHEMBL23826099 | 0.87 | DPP4 (0.62) | DPP4HPGDRECQLEPHX1GPR119 | |
| SCHEMBL23826102 | 0.87 | DPP4 (0.62) | DPP4HPGDRECQLEPHX1GPR119 | |
| SCHEMBL23826056 | 0.85 | DPP4 (0.64) | DPP4HPGDRECQLEPHX1GPR119 | |
| SCHEMBL14622829 | 0.85 | DPP4 (0.64) | DPP4HPGDRECQLEPHX1GPR119 | |
| SCHEMBL148385 | 0.84 | GPR119 (0.53) | DPP4HPGDRECQLEPHX1NR1H2 | |
| SCHEMBL21995203 | 0.84 | HPGD (0.48) | DPP4HPGDRECQLEPHX1NR1H2 | |
| SCHEMBL1576175 | 0.84 | GPR119 (0.53) | DPP4HPGDRECQLEPHX1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272905-A | Piperidine compound and preparation method thereof | TIANJIN SPHINX DRUG RES AND DEV CO LTD | 2016-01-27 | — | — | CN | claimed |
| CN-105272905-B | A kind of piperidine compounds and preparation method thereof | 天津市斯芬克司药物研发有限公司 | 2017-12-19 | — | — | CN | disclosed |
| CN-105272905-A | Piperidine compound and preparation method thereof | TIANJIN SPHINX DRUG RES AND DEV CO LTD | 2016-01-27 | — | — | CN | disclosed |