Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28566126 | 1.00 | ATM (0.32) | ATMCYP1A1CYP1A2CYP1B1JAK2 | |
| SCHEMBL28566127 | 1.00 | ATM (0.32) | ATMCYP1A1CYP1A2CYP1B1JAK2 | |
| SCHEMBL28687368 | 0.90 | ATM (0.30) | ATM | |
| SCHEMBL28194300 | 0.76 | NAAA (0.33) | — | |
| SCHEMBL14527954 | 0.75 | — | — | |
| SCHEMBL8438426 | 0.74 | ATM (0.39) | ATM | |
| SCHEMBL20337044 | 0.74 | ATM (0.34) | ATM | |
| SCHEMBL20337045 | 0.74 | ATM (0.34) | ATM | |
| SCHEMBL26924050 | 0.73 | — | — | |
| SCHEMBL425737 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189520-B | Carbostyril derivative | 埃科特莱茵药品有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-105189520-A | Quinolone derivatives | ACTELION PHARMACEUTICALS LTD | 2015-12-23 | — | — | CN | disclosed |