Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NME2 | P22392 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045595 | 0.86 | MEN1 (0.66) | KMT2AMEN1 | |
| SCHEMBL10853060 | 0.81 | KMT2A (0.55) | RAB9AMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL10849598 | 0.80 | KMT2A (0.56) | RAB9ANPC1ALOX5MAPTKMT2A | |
| SCHEMBL29519449 | 0.80 | NPC1 (0.62) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL29519532 | 0.79 | RAB9A (0.68) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL21992755 | 0.79 | RAB9A (1.00) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL14882372 | 0.79 | RAB9A (1.00) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL11086290 | 0.79 | NPC1 (0.61) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL11086293 | 0.79 | NPC1 (0.61) | RAB9ANPC1ALOX5MAPTCCR3 | |
| SCHEMBL10851747 | 0.78 | KMT2A (0.54) | RAB9ANPC1ALOX5MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272986-A | A compound for inhibiting acetylcholinesterase activity, and preparation method and uses thereof | XIAMEN MEDICAL COLLEGE | 2016-01-27 | — | — | CN | disclosed |