Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045721 | 1.00 | FOLH1 (0.63) | FOLH1PPARAMMEPPARGCNR2 | |
| SCHEMBL12989752 | 0.88 | FOLH1 (0.63) | FOLH1PPARAMMEPPARGS1PR1 | |
| SCHEMBL27932795 | 0.87 | FOLH1 (0.61) | FOLH1PPARAMMEPPARGS1PR1 | |
| SCHEMBL27932798 | 0.87 | FOLH1 (0.61) | FOLH1PPARAMMEPPARGS1PR1 | |
| SCHEMBL11313609 | 0.85 | FOLH1 (0.60) | FOLH1PPARAMMEPPARGS1PR1 | |
| SCHEMBL11313605 | 0.85 | FOLH1 (0.60) | FOLH1PPARAMMEPPARGS1PR1 | |
| SCHEMBL1942200 | 0.83 | FOLH1 (0.64) | FOLH1PPARAMMEPPARGSLC1A1 | |
| SCHEMBL9831124 | 0.83 | CNR2 (0.55) | CNR2ITGB3ITGA2BCTSLCTSB | |
| SCHEMBL9831119 | 0.83 | CNR2 (0.55) | CNR2ITGB3ITGA2BCTSLCTSB | |
| SCHEMBL6931337 | 0.83 | FOLH1 (0.64) | FOLH1PPARAMMEPPARGSLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175418-B | Pentacyclic indole quinolizine for inhibiting autophagy of cells, synthesis, antitumor activity and application thereof | 首都医科大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-105175418-A | Pentacyclic indole quinolizine inhibiting cell autophagy, synthesis, antitumor activity and application thereof | UNIV CAPITAL MEDICAL SCIENCES | 2015-12-23 | — | — | CN | disclosed |