SCHEMBL12989752

SCHEMBL12989752

O=C(CI)NC(COCc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.63
PPARA Q07869 2/20 0.57
MME P08473 1/20 0.55
PPARG P37231 1/20 0.52
SLC1A1 P43005 1/20 0.48
MMP9 P14780 1/20 0.47
MMP14 P50281 1/20 0.47
S1PR1 P21453 3/20 0.46
CTSS P25774 1/20 0.45
CA1 P00915 3/20 0.44
CA2 P00918 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GPR34 Q9UPC5 1/20 0.43
GPR132 Q9UNW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28045721 0.88 FOLH1 (0.63) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL28045720 0.88 FOLH1 (0.63) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL27932795 0.87 FOLH1 (0.61) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL27932798 0.87 FOLH1 (0.61) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL6931337 0.83 FOLH1 (0.64) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL28001170 0.83 FOLH1 (0.64) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL14284252 0.83 FOLH1 (0.64) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL1942200 0.83 FOLH1 (0.64) FOLH1PPARAMMEPPARGSLC1A1
SCHEMBL1024175 0.82 PPARA (0.64) FOLH1PPARAMMEPPARGCTSS
SCHEMBL16418003 0.82 FOLH1 (0.63) FOLH1PPARAMMEPPARGCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8501498-B2 Mass tags for quantitative analyses DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2013-08-06 US disclosed
US-20100311175-A1 MASS TAGS FOR QUANTITATIVE ANALYSES Life Technologies Corporation (US) 2010-12-09 US disclosed
US-20100311175-A1 MASS TAGS FOR QUANTITATIVE ANALYSES Life Technologies Corporation (US) 2010-12-09 US disclosed
US-20070048752-A1 Mass tags for quantitative analyses APPLERA CORPORATION (US) 2007-03-01 US disclosed
US-20070048752-A1 Mass tags for quantitative analyses APPLERA CORPORATION (US) 2007-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311175-A1 MASS TAGS FOR QUANTITATIVE ANALYSES SRMS, PTMS, TMT1A FOLH1 825/4885PPARA 3238/4885MME 200/4885
US-20070048752-A1 Mass tags for quantitative analyses SRMS, PTMS, TMT1A FOLH1 825/4885PPARA 3238/4885MME 200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.