Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 16/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841578 | 0.84 | SCN9A (0.63) | SCN9ACHRM5 | |
| SCHEMBL4597269 | 0.83 | SCN9A (0.77) | SCN9ACHRM5OPRL1 | |
| SCHEMBL20988966 | 0.83 | SCN9A (0.83) | SCN9ACHRM5 | |
| SCHEMBL2357070 | 0.82 | SCN9A (0.60) | SCN9ACHRM5OPRL1 | |
| SCHEMBL4597672 | 0.81 | SCN9A (1.00) | SCN9ACHRM5OPRL1 | |
| SCHEMBL2308969 | 0.80 | SCN9A (0.57) | SCN9ACHRM5OPRL1 | |
| SCHEMBL4597136 | 0.79 | SCN9A (0.89) | SCN9A | |
| SCHEMBL4598042 | 0.78 | SCN9A (0.70) | SCN9ACHRM5 | |
| SCHEMBL4727817 | 0.77 | SCN9A (0.76) | SCN9ACHRM5 | |
| SCHEMBL30951950 | 0.77 | SCN9A (0.76) | SCN9ACHRM5OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218565-A | Spiral shell oxindole compounds and the purposes as therapeutical agent thereof | XENON PHARMACEUTICALS INC | 2016-01-06 | — | — | CN | disclosed |
| CN-105175433-A | Spiro-oxindole compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC | 2015-12-23 | — | — | CN | disclosed |