Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 14/20 | 0.76 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30951949 | 1.00 | SCN9A (0.76) | SCN9ACHRM5CA12CA1CA2 | |
| SCHEMBL30951963 | 0.87 | SCN9A (0.57) | SCN9ACHRM5 | |
| SCHEMBL30951993 | 0.86 | SCN9A (0.62) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951997 | 0.86 | SCN9A (0.62) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951988 | 0.86 | SCN9A (0.60) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL20988966 | 0.86 | SCN9A (0.83) | SCN9ACHRM5 | |
| SCHEMBL4597672 | 0.86 | SCN9A (1.00) | SCN9ACHRM5OPRL1 | |
| SCHEMBL30951961 | 0.86 | SCN9A (0.55) | SCN9ACHRM5CA12CA1CA2 | |
| SCHEMBL30951992 | 0.84 | SCN9A (0.56) | SCN9ACA12CA1CA2CA9 | |
| SCHEMBL30951998 | 0.83 | SCN9A (0.56) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630401-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | Rutgers, the State University of New Jersey (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124023-A2 | CARBONIC ANHYDRASE ENZYME INHIBITORS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2024-06-13 | — | — | WO | disclosed |