Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322144 | 0.94 | HPGD (0.41) | NPC1RAB9AALDH1A1HPGDPKM | |
| SCHEMBL28045857 | 0.76 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15067896 | 0.75 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19254537 | 0.75 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28045844 | 0.75 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28320994 | 0.74 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL25214867 | 0.72 | GLA (0.51) | NPC1RAB9ASMN1; SMN2EPHX1HDAC3 | |
| SCHEMBL15067052 | 0.71 | MEN1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11123663 | 0.70 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1FAAH | |
| SCHEMBL27630590 | 0.68 | HDAC3 (0.62) | NPC1RAB9ASMN1; SMN2EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189450-A | Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same | BIO PHARM SOLUTIONS CO LTD | 2015-12-23 | — | — | CN | claimed |
| CN-105189450-B | Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same | 比皮艾思药物研发有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-105189450-A | Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same | BIO PHARM SOLUTIONS CO LTD | 2015-12-23 | — | — | CN | disclosed |