Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045857 | 0.82 | SMN1; SMN2 (0.49) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15067896 | 0.78 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28045844 | 0.78 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19254537 | 0.78 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28322144 | 0.77 | HPGD (0.41) | NPC1RAB9AALDH1A1EPHX2HPGD | |
| SCHEMBL28045877 | 0.74 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28321127 | 0.73 | ADRB2 (0.44) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28045872 | 0.72 | RAB9A (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17365405 | 0.71 | USP2 (0.41) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL17790872 | 0.71 | ACHE (0.44) | NPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189450-B | Phenyl carbamate compound and composition for preventing or treating mental disorder comprising the same | 比皮艾思药物研发有限公司 | 2019-09-13 | — | — | CN | disclosed |