Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | LOX | P28300 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374632 | 0.87 | PTPN1 (0.69) | RIPK2RAB9ASMN1; SMN2TSHRPTPN1 | |
| SCHEMBL4696735 | 0.84 | RIPK2 (0.71) | RIPK2RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL1692019 | 0.84 | RIPK2 (0.71) | RIPK2RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL3830233 | 0.84 | RIPK2 (0.71) | RIPK2RAB9ASMN1; SMN2LMNAPTPN1 | |
| SCHEMBL2743084 | 0.83 | RIPK2 (1.00) | RIPK2RAB9ASMN1; SMN2LMNAMAPK14 | |
| SCHEMBL2834342 | 0.83 | RIPK2 (0.70) | RIPK2RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL7510664 | 0.83 | KMT2A (0.56) | RIPK2RAB9ATSHRPTGS2ALDH1A1 | |
| SCHEMBL2786396 | 0.80 | MAPK14 (0.70) | RIPK2RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL18216831 | 0.80 | RIPK2 (0.66) | RIPK2RAB9ASMN1; SMN2LMNATSHR | |
| SCHEMBL4883305 | 0.79 | MAPT (0.57) | RIPK2RAB9ASMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |