Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376392 | 0.88 | HTT (0.67) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL15933265 | 0.87 | HTT (0.69) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL8050439 | 0.87 | RIPK2 (0.72) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL3427893 | 0.84 | RIPK2 (0.68) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL3761319 | 0.84 | RIPK2 (0.68) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL1691418 | 0.84 | MAPK14 (0.72) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL15930131 | 0.83 | HTT (0.65) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL2804588 | 0.83 | RIPK2 (0.71) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL8050422 | 0.83 | RIPK2 (0.71) | RIPK2HTTRAB9ALMNASMN1; SMN2 | |
| SCHEMBL2743084 | 0.83 | RIPK2 (1.00) | RIPK2RAB9ALMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |