SCHEMBL28045965

SCHEMBL28045965

O=[N+]([O-])c1ccc(S(=O)(=O)NC2CC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.61
RECQL P46063 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KMT2A Q03164 3/20 0.60
TDP1 Q9NUW8 2/20 0.60
MEN1 O00255 2/20 0.60
POLB P06746 1/20 0.60
CA2 P00918 3/20 0.58
CA1 P00915 2/20 0.58
CA12 O43570 2/20 0.58
CA9 Q16790 2/20 0.58
MMP1 P03956 1/20 0.58
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
CA3 P07451 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
CA5A P35218 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20271516 0.93 SMN1; SMN2 (0.73) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL5723140 0.93 SMN1; SMN2 (0.68) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL23093557 0.92 CA1 (0.54) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL15225951 0.92 SMN1; SMN2 (0.71) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL1879475 0.89 MEN1 (0.53) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL27221141 0.89 MEN1 (0.53) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL12971126 0.88 ALDH1A1 (0.68) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL12971127 0.88 ALDH1A1 (0.68) KDM4ERECQLSMN1; SMN2KMT2ATDP1
SCHEMBL3668793 0.86 CA1 (0.51) KDM4ERECQLSMN1; SMN2KMT2ATDP1
Bicarbonate SCHEMBL15226074 0.86 SMN1; SMN2 (0.63) KDM4ERECQLSMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024025389-A1 METHOD FOR PREPARING INTERMEDIATE OF PHTHALAZINONE DERIVATIVE 아이디언스 주식회사 2024-02-01 WO claimed
EP-4719413-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF Animol Discovery, Inc. (US) 2026-04-08 EP disclosed
WO-2024246837-A1 INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF ANIMOL DISCOVERY, INC. (US) 2024-12-05 WO disclosed
WO-2024025389-A1 METHOD FOR PREPARING INTERMEDIATE OF PHTHALAZINONE DERIVATIVE 아이디언스 주식회사 2024-02-01 WO disclosed
CN-105209031-A Novel antiviral agents against HBV infection UNIV DREXEL 2015-12-30 CN disclosed