Fluorene

Fluorene

SCHEMBL28045968

C=C(C)C(=O)O.Oc1ccccc1.Oc1ccccc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.47
MAOA P21397 2/20 0.46
CYP1A2 P05177 2/20 0.46
HTR2C P28335 2/20 0.46
HTR2B P41595 2/20 0.46
ADRA2A P08913 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46
NPC1 O15118 4/20 0.43
RAB9A P51151 4/20 0.43
ALDH1A1 P00352 3/20 0.42
MIF P14174 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
HSD17B1 P14061 1/20 0.39
KDM4E B2RXH2 2/20 0.39
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL4600798 1.00 SRD5A2 (0.47) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL29848606 0.93 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL1151459 0.93 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL2127827 0.93 SRD5A2 (0.53) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL21084447 0.86 SRD5A2 (0.47) SRD5A2MAOACYP1A2HTR2CHTR2B
Phenol SCHEMBL29093494 0.84 PNMT (0.49) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL28197022 0.83 SRD5A2 (0.45) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL28246971 0.83 SRD5A2 (0.45) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL233215 0.83 CA12 (0.55) SRD5A2MAOACYP1A2HTR2CHTR2B
Fluorene SCHEMBL441983 0.83 CA12 (0.55) SRD5A2MAOACYP1A2HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105175607-B A kind of high index of refraction lens resin monomer material 寿光市鲁源盐化有限公司 2017-07-14 CN claimed
CN-108456451-A A kind of dual cure plate glass ink and preparation method thereof 滁州金桥德克新材料有限公司 2018-08-28 CN disclosed
CN-105175607-B A kind of high index of refraction lens resin monomer material 寿光市鲁源盐化有限公司 2017-07-14 CN disclosed
CN-105175607-A High-refractivity lens resin monomer material SHOUGUANG LUYUAN SALT CHEMICAL CO LTD 2015-12-23 CN disclosed