Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127560 | 0.76 | CYP1A2 (0.48) | KMT2AMEN1CASP1KDM4EHSD17B10 | |
| SCHEMBL27798244 | 0.75 | RXFP1 (0.43) | KDM4EALDH1A1NPC1RAB9ANPSR1 | |
| SCHEMBL11782094 | 0.74 | KMT2A (0.49) | KMT2AMEN1HSD17B10MAPK1CYP3A4 | |
| SCHEMBL20049003 | 0.73 | MEN1 (0.44) | KMT2AMEN1KDM4EHSD17B10MAPK1 | |
| SCHEMBL27834650 | 0.72 | KMT2A (0.51) | KMT2AMEN1MAPK1CYP3A4TSHR | |
| SCHEMBL18506525 | 0.71 | MEN1 (0.50) | KMT2AMEN1KDM4EHSD17B10MAPK1 | |
| SCHEMBL3562718 | 0.71 | MEN1 (0.53) | KMT2AMEN1HSD17B10MAPK1ALDH1A1 | |
| SCHEMBL5972595 | 0.71 | KMT2A (0.56) | KMT2AMEN1CASP1KDM4EHSD17B10 | |
| SCHEMBL9271743 | 0.70 | ALDH1A1 (0.67) | KMT2AMEN1CASP1KDM4EHSD17B10 | |
| SCHEMBL31370710 | 0.70 | KMT2A (0.55) | KMT2AMEN1CASP1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228983-A | The compound regulated for kinases and indication thereof | PLEXXIKON INC | 2016-01-06 | — | — | CN | disclosed |