Acrylamide

Acrylamide

SCHEMBL28046099

C=CC(=O)NC(C)(C)CC(=O)O.C=CC(N)=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
CYP2C19 P33261 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TSHR P16473 4/20 0.41
FGFR4 P22455 1/20 0.41
HMGCR P04035 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
CYP2D6 P10635 1/20 0.34
HIF1A Q16665 1/20 0.34
MAPK1 P28482 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35674 0.92 ALDH1A1 (0.56) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Hydrochloric Acid SCHEMBL7158460 0.90 ALDH1A1 (0.54) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
SCHEMBL9246722 0.90 ALDH1A1 (0.54) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Dimethylamine SCHEMBL9133373 0.87 ALDH1A1 (0.51) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Dimethylamine SCHEMBL9133610 0.87 ALDH1A1 (0.51) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Acrylamide SCHEMBL11572641 0.84 ALDH1A1 (0.45) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
SCHEMBL17266437 0.79 CYP2C19 (0.46) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Hydrochloric Acid SCHEMBL9133471 0.78 ALDH1A1 (0.44) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
Acrylamide SCHEMBL998819 0.78 ALDH1A1 (0.50) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1
SCHEMBL31376272 0.78 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP3A4CYP2C9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105199530-A Super-hydrophilic polyacrylamide coating and preparation method thereof CHINESE ACAD TECH INST PHYSICS 2015-12-30 CN disclosed