Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880578 | 0.79 | PARP1 (0.44) | PARP1KDM4E | |
| SCHEMBL26964134 | 0.75 | PARP1 (0.44) | PARP1KDM4E | |
| SCHEMBL8838482 | 0.74 | PDE10A (0.44) | PARP1KDM4E | |
| SCHEMBL26964265 | 0.73 | KDM4E (0.67) | PARP1KDM4E | |
| SCHEMBL3708915 | 0.68 | KDM4E (0.37) | PARP1KDM4ETSHR | |
| SCHEMBL10321093 | 0.68 | BACE1 (0.39) | PARP1KDM4ETSHR | |
| SCHEMBL31588980 | 0.68 | KDM4E (0.37) | PARP1KDM4EIDO1TSHR | |
| SCHEMBL8489038 | 0.68 | KDM4E (0.44) | PARP1KDM4E | |
| SCHEMBL29800848 | 0.68 | KDM4E (0.62) | PARP1KDM4E | |
| SCHEMBL2197162 | 0.68 | KMT2A (0.41) | PARP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102958918-B | Novel tobacco amide derivatives or its salt | FUJIFILM CORP. (JP) | 2015-12-09 | — | — | CN | disclosed |