Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099182 | 0.81 | PDE4A (0.40) | PARP1HPGDSGRM5KDM4EPSMD14 | |
| SCHEMBL8811070 | 0.81 | HPGDS (0.56) | PDE10APARP1HPGDSTDP1LMNA | |
| SCHEMBL7589324 | 0.81 | KDM4E (0.57) | PDE10APARP1KDM4E | |
| SCHEMBL16880578 | 0.80 | PARP1 (0.44) | PDE10APARP1KDM4ETDP1LMNA | |
| SCHEMBL8838403 | 0.77 | PDE10A (0.51) | PDE10APARP1KDM4ETDP1LMNA | |
| SCHEMBL28076889 | 0.77 | PARP1 (0.56) | PARP1HPGDSKDM4ELMNAPSMD14 | |
| SCHEMBL26964134 | 0.76 | PARP1 (0.44) | PDE10APARP1KDM4ETDP1LMNA | |
| SCHEMBL10320559 | 0.76 | PARP1 (0.45) | PDE10APARP1HPGDSKDM4E | |
| SCHEMBL28046381 | 0.74 | PARP1 (0.40) | PARP1KDM4E | |
| SCHEMBL3150525 | 0.73 | CYP1A2 (0.52) | PDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1089758-C | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID CO (US) | 2002-08-28 | — | — | CN | disclosed |
| US-5625068-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| CN-1138035-A | Substituted quinoline herbicide intermediates and process | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | CN | disclosed |
| EP-0747361-A1 | Substituted quinoline herbicide intermediates and process | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |