Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939712 | 0.81 | ABL1 (0.66) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL28046472 | 0.79 | ABL1 (0.62) | ABL1 | |
| SCHEMBL28046496 | 0.78 | ABL1 (0.53) | ABL1 | |
| SCHEMBL28046485 | 0.78 | ABL1 (0.60) | ABL1 | |
| SCHEMBL14244874 | 0.77 | ABL1 (0.59) | ABL1 | |
| SCHEMBL28046448 | 0.77 | ABL1 (0.66) | ABL1 | |
| SCHEMBL14244604 | 0.77 | ABL1 (0.76) | ABL1 | |
| SCHEMBL28046460 | 0.75 | ABL1 (0.67) | ABL1 | |
| SCHEMBL9939286 | 0.75 | ABL1 (0.49) | ABL1 | |
| SCHEMBL28046468 | 0.74 | ABL1 (0.75) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |