Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 19/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28046472 | 0.93 | ABL1 (0.62) | ABL1MAPK14 | |
| SCHEMBL28046485 | 0.91 | ABL1 (0.60) | ABL1MAPK14 | |
| SCHEMBL28046474 | 0.86 | ABL1 (0.68) | ABL1LCKCSF1RKDRMAPK14 | |
| SCHEMBL28046460 | 0.85 | ABL1 (0.67) | ABL1LCKCSF1RKDRMAPK14 | |
| SCHEMBL28046468 | 0.85 | ABL1 (0.75) | ABL1 | |
| SCHEMBL28046448 | 0.83 | ABL1 (0.66) | ABL1 | |
| SCHEMBL28046463 | 0.82 | ABL1 (0.70) | ABL1LCKCSF1RKDRMAPK14 | |
| SCHEMBL28046442 | 0.82 | ABL1 (0.70) | ABL1LCKCSF1RKDRMAPK14 | |
| SCHEMBL9939316 | 0.79 | ABL1 (0.65) | ABL1LCKCSF1RKDRMAPK14 | |
| SCHEMBL9939286 | 0.79 | ABL1 (0.49) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261167-B | 6 of replacement, 6-condenses nitrogen-containing heterocycle compound and uses thereof | HOFFMAN-LA ROCHE LTD. (CH) | 2016-05-04 | — | — | CN | disclosed |