Pyrrole

Pyrrole

SCHEMBL28046493

C1=CNc2ccccc2C=N1.c1cc[nH]c1

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL211612 0.90 GAA (0.36) GAAMAPT
Hydrochloric Acid SCHEMBL2360762 0.88 GAA (0.34) GAAMAPT
SCHEMBL28185725 0.88 GAA (0.34) GAAMAPT
SCHEMBL29157769 0.88 GAA (0.34) GAAMAPT
SCHEMBL28157348 0.88 GAA (0.34) GAAMAPT
Hydrochloric Acid SCHEMBL3772181 0.88 GAA (0.34) GAAMAPT
Hydrochloric Acid SCHEMBL28292448 0.86 GAA (0.33) GAAMAPT
SCHEMBL29141748 0.83 GAA (0.31) GAAMAPT
Biphenyl SCHEMBL27476421 0.83 ALDH1A1 (0.35) GAAMAPT
Phosphoric Acid SCHEMBL28309458 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107847568-A The anti-antibody of CLL 1 and application method 豪夫迈·罗氏有限公司 2018-03-27 CN disclosed
CN-103641834-B Pyrrolobenzodiazepines * compounds and its preparation method and application SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2015-12-09 CN disclosed