Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16031035 | 0.88 | HSD17B10 (0.39) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL16148112 | 0.79 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL16031033 | 0.79 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL16031037 | 0.79 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL22341351 | 0.79 | MMP2 (0.35) | — | |
| SCHEMBL21408171 | 0.72 | DPP4 (0.35) | HPGD | |
| SCHEMBL4748069 | 0.71 | MAPK1 (0.32) | MAPK1HPGDBTK | |
| SCHEMBL21408159 | 0.71 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL29775769 | 0.71 | HSD17B10 (0.42) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL17631948 | 0.70 | HSD17B10 (0.38) | HSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228995-A | The piperidine compounds replaced and they are as the purposes of orexin receptor conditioning agent | JANSSEN PHARMACEUTICA NV | 2016-01-06 | — | — | CN | disclosed |