Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.56 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.56 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.56 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6086484 | 0.90 | KCNQ3 (0.56) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL28046564 | 0.89 | KCNQ3 (0.55) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL6085966 | 0.88 | KCNQ3 (0.55) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL28046562 | 0.88 | HDAC8 (0.64) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15601460 | 0.88 | KCNQ3 (0.56) | HDAC8HDAC6KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL15601447 | 0.86 | KCNQ3 (0.53) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15601462 | 0.86 | EPHX2 (0.64) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15601409 | 0.86 | KCNQ3 (0.65) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15601468 | 0.85 | KCNQ3 (0.53) | HDAC8HDAC6KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL15601449 | 0.85 | KCNQ3 (0.55) | HDAC8HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103554008-B | 1,3-replacement-5-acetylamino indole ketone compound and the application in antineoplastic thereof | TIANJIN UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2016-05-04 | — | — | CN | disclosed |