Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.65 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.65 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 10/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17154046 | 0.92 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL17154061 | 0.89 | KCNQ3 (0.66) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL15601466 | 0.88 | KCNQ3 (0.65) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL6086484 | 0.86 | KCNQ3 (0.56) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL28046571 | 0.86 | HDAC8 (0.58) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL15601431 | 0.86 | KCNQ3 (0.63) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL28046564 | 0.85 | KCNQ3 (0.55) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL6085966 | 0.85 | KCNQ3 (0.55) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL15601449 | 0.85 | KCNQ3 (0.55) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 | |
| SCHEMBL15601460 | 0.84 | KCNQ3 (0.56) | KCNQ3KCNQ2KCNQ4KCNQ5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9321750-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-9321750-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-04-26 | — | — | US | disclosed |
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-10-08 | — | — | US | disclosed |
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-10-08 | — | — | US | disclosed |
| WO-2013159095-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284366-A1 | ROR MODULATORS AND THEIR USES | RORA, RORB, RORC | KCNQ3 3019/4885KCNQ2 3011/4885KCNQ4 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.