Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12928169 | 0.84 | PIK3CA (0.52) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL12850681 | 0.80 | LMNA (0.66) | NPC1RAB9AL3MBTL1PIK3CAPIK3CD | |
| SCHEMBL14097677 | 0.79 | GAA (0.65) | NPC1RAB9ASMN1; SMN2L3MBTL1PIK3CA | |
| SCHEMBL31119195 | 0.79 | GAA (0.65) | NPC1RAB9ASMN1; SMN2L3MBTL1PIK3CA | |
| Hydrochloric Acid SCHEMBL7229219 | 0.75 | CCR1 (0.47) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL25244451 | 0.75 | MAPT (0.47) | NPC1TP53RAB9ASMN1; SMN2PIK3CA | |
| SCHEMBL26023362 | 0.75 | SMN1; SMN2 (0.68) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28914009 | 0.74 | NPC1 (0.59) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL30386364 | 0.74 | NPC1 (0.59) | NPC1TP53RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL12928599 | 0.74 | PIK3CG (0.58) | NPC1RAB9ASMN1; SMN2L3MBTL1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130973-B | 5- pyridine radicals -2- amino-benzo [d] oxazole derivatives and its preparation method and application | 海南国瑞堂中药制药有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-105130973-A | 5-Pyridyl-2-amino-benzo[d]oxazole derivatives, and preparation method and use thereof | HAINAN GRTANG TRADITIONAL CHINESE MEDICINE PHARMACEUTICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-105130973-A | 5-Pyridyl-2-amino-benzo[d]oxazole derivatives, and preparation method and use thereof | HAINAN GRTANG TRADITIONAL CHINESE MEDICINE PHARMACEUTICAL CO LTD | 2015-12-09 | — | — | CN | disclosed |