Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604414 | 0.89 | TSHR (0.46) | TSHRALDH1A1L3MBTL1ESR2HPGD | |
| SCHEMBL343227 | 0.83 | TSHR (0.46) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL536175 | 0.83 | TSHR (0.46) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL25409749 | 0.81 | TSHR (0.41) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL10470446 | 0.81 | L3MBTL1 (0.44) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL11603745 | 0.80 | TSHR (0.47) | TSHRALDH1A1L3MBTL1HPGDADRA2A | |
| SCHEMBL28715842 | 0.79 | TSHR (0.44) | TSHRALDH1A1L3MBTL1ESR2HPGD | |
| SCHEMBL29835035 | 0.79 | TSHR (0.50) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL254017 | 0.79 | TSHR (0.50) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 | |
| Ethane SCHEMBL2154170 | 0.77 | TSHR (0.48) | TSHRALDH1A1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330565-B | Novel method for catalytically synthesizing cyanobenzene derivative through copper | 杭州师范大学 | 2017-05-24 | — | — | CN | disclosed |
| CN-105330565-A | Novel method for catalytically synthesizing cyanobenzene derivative through copper | UNIV HANGZHOU NORMAL | 2016-02-17 | — | — | CN | disclosed |