Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.34 |
| ▸ | CCR6 | P51684 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868453 | 0.98 | SPHK2 (0.37) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL5868456 | 0.98 | SPHK2 (0.37) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL7118583 | 0.85 | SPHK2 (0.42) | SPHK2SPHK1CETPMAPTMEN1 | |
| SCHEMBL7118580 | 0.85 | SPHK2 (0.42) | SPHK2SPHK1CETPMAPTMEN1 | |
| SCHEMBL18669173 | 0.84 | TAS1R3 (0.39) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL16689753 | 0.84 | TAS1R3 (0.39) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL19628508 | 0.84 | TAS1R3 (0.39) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL28657762 | 0.81 | HDAC2 (0.33) | THRB | |
| SCHEMBL14334738 | 0.80 | SPHK2 (0.37) | SPHK2SPHK1CETPMAPTTRPA1 | |
| SCHEMBL8185806 | 0.80 | MEN1 (0.46) | SPHK2SPHK1CETPMAPTTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085565-B | A kind of preparation method of hydroxypropyl (fourth) base disiloxane | 山东大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-105085565-A | Preparation method for hydroxypropyl (butyl) disiloxane | UNIV SHANDONG | 2015-11-25 | — | — | CN | disclosed |