Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13173500 | 0.89 | KMT2A (0.63) | MEN1KMT2AKDM4EMAPTHPGD | |
| SCHEMBL4001714 | 0.89 | KDM4E (0.53) | ALDH1A3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL22198778 | 0.84 | ADORA2A (0.46) | ALDH1A3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20222411 | 0.84 | MEN1 (0.55) | ALDH1A3MEN1KMT2AACHEKDM4E | |
| SCHEMBL19287955 | 0.83 | MEN1 (0.55) | ALDH1A3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL20220277 | 0.82 | MEN1 (0.77) | ALDH1A3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4357711 | 0.82 | MEN1 (0.77) | ALDH1A3MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4355827 | 0.82 | MAPT (0.65) | ALDH1A3MEN1KMT2AACHEKDM4E | |
| SCHEMBL31291015 | 0.82 | MAPT (0.65) | ALDH1A3MEN1KMT2AACHEKDM4E | |
| SCHEMBL16376447 | 0.82 | MEN1 (0.77) | ALDH1A3MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105237466-A | Method for compounding tri-substituted pyridine derivatives | UNIV NANYANG NORMAL | 2016-01-13 | — | — | CN | claimed |
| CN-105237466-B | A kind of method for synthesizing three substituted pyridine derivatives | 南阳师范学院 | 2017-08-25 | — | — | CN | disclosed |
| CN-105237466-A | Method for compounding tri-substituted pyridine derivatives | UNIV NANYANG NORMAL | 2016-01-13 | — | — | CN | disclosed |