Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK1 | P06870 | 9/20 | 0.68 |
| ▸ | KLKB1 | P03952 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047225 | 0.90 | KLKB1 (0.68) | KLK1KLKB1 | |
| SCHEMBL16247145 | 0.87 | KLKB1 (0.69) | KLK1KLKB1 | |
| SCHEMBL28047171 | 0.84 | KLKB1 (0.62) | KLK1KLKB1 | |
| SCHEMBL15874021 | 0.81 | KLK1 (1.00) | KLK1KLKB1 | |
| SCHEMBL28825219 | 0.80 | KLKB1 (0.65) | KLK1KLKB1 | |
| SCHEMBL28047221 | 0.80 | KLKB1 (0.64) | KLK1KLKB1 | |
| SCHEMBL28047298 | 0.80 | KLKB1 (0.68) | KLK1KLKB1 | |
| SCHEMBL28047228 | 0.80 | KLKB1 (0.59) | KLK1KLKB1 | |
| SCHEMBL28047219 | 0.79 | KLKB1 (0.71) | KLK1KLKB1 | |
| SCHEMBL28047231 | 0.79 | KLKB1 (0.58) | KLK1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | claimed |
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |