Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.58 |
| ▸ | KLK1 | P06870 | 10/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28047228 | 0.89 | KLKB1 (0.59) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL16247145 | 0.87 | KLKB1 (0.69) | KLKB1KLK1 | |
| SCHEMBL28047219 | 0.83 | KLKB1 (0.71) | KLKB1KLK1 | |
| SCHEMBL28047225 | 0.80 | KLKB1 (0.68) | KLKB1KLK1 | |
| SCHEMBL28047174 | 0.80 | KLKB1 (0.50) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28047301 | 0.80 | KLKB1 (0.58) | KLKB1KLK1 | |
| SCHEMBL28047229 | 0.79 | KLK1 (0.68) | KLKB1KLK1 | |
| SCHEMBL28825220 | 0.79 | KLKB1 (0.56) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL28047227 | 0.75 | KLKB1 (0.55) | KLKB1KLK1NR1I2KCNH2GRM2 | |
| SCHEMBL15874062 | 0.74 | KLKB1 (1.00) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | claimed |
| CN-105143201-A | Benzylamine derivatives | KALVISTA PHARMACEUTICALS LTD | 2015-12-09 | — | — | CN | disclosed |