Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NEU2 | Q9Y3R4 | 2/20 | 0.37 |
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.37 |
| ▸ | NEU1 | Q99519 | 1/20 | 0.37 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15661267 | 1.00 | PDE4A (0.41) | PDE4ALMNANEU2NEU4NEU1 | |
| SCHEMBL15661773 | 1.00 | PDE4A (0.41) | PDE4ALMNANEU2NEU4NEU1 | |
| SCHEMBL29116406 | 0.89 | NEU2 (0.38) | NEU2NEU4NEU1NEU3 | |
| SCHEMBL15662367 | 0.89 | NEU2 (0.38) | NEU2NEU4NEU1NEU3 | |
| SCHEMBL15658717 | 0.89 | NEU2 (0.38) | NEU2NEU4NEU1NEU3 | |
| SCHEMBL28887069 | 0.81 | NEU2 (0.39) | PDE4ALMNANEU2NEU4NEU1 | |
| SCHEMBL4862153 | 0.77 | PDE4A (0.48) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL30407499 | 0.76 | LMNA (0.46) | PDE4ALMNANEU2NEU4NEU1 | |
| SCHEMBL18209366 | 0.74 | PDE4A (0.46) | PDE4ALMNAL3MBTL1TDP1USP2 | |
| SCHEMBL29171639 | 0.74 | PDE4A (0.48) | PDE4ALMNAL3MBTL1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925228-A | Modified PD-1 antibody and preparation method and application thereof | 苏州大学 | 2023-10-24 | — | — | CN | disclosed |
| CN-108883191-B | Antibody-conjugates with improved therapeutic index for targeting CD30 tumors and methods for improving the therapeutic index of antibody-conjugates | 西纳福克斯股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113943330-A | Sugar-containing structure compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-01-18 | — | — | CN | disclosed |
| CN-105142672-A | Modified antibodies, antibody-conjugates and methods of making the same | SYNAFFIX BV | 2015-12-09 | — | — | CN | disclosed |