Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 3/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582562 | 0.94 | SCN1A (0.53) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL8592701 | 0.90 | SCN1A (0.67) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL28319844 | 0.89 | CYP3A4 (0.62) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL28335137 | 0.88 | CYP3A4 (0.60) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL13963989 | 0.85 | KCNN4 (0.53) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL8675347 | 0.84 | SCN1A (0.49) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL27941514 | 0.84 | PIN1 (0.47) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL8050248 | 0.84 | SMN1; SMN2 (0.48) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL28970082 | 0.83 | CHRM2 (0.65) | SCN1ASCN2ASCN3ALMNACYP1A2 | |
| SCHEMBL14380533 | 0.83 | SCN1A (0.48) | SCN1ASCN2ASCN3ALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104159884-B | The method of compound is prepared as the novel reversal of the Michael addition of additive by using water or multiple acid | LG LIFE SCIENCES LTD. (KR) | 2016-01-13 | — | — | CN | disclosed |