Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887321 | 0.74 | KDM4E (0.45) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL13026806 | 0.74 | LMNA (0.41) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL13067325 | 0.74 | LMNA (0.42) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL11327834 | 0.74 | LMNA (0.41) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL22463402 | 0.74 | LMNA (0.41) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL18659115 | 0.74 | LMNA (0.41) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL28656434 | 0.74 | TDP1 (0.38) | KDM4ECYP1A2GRIA1GRIA2GRIA3 | |
| SCHEMBL29907308 | 0.74 | KDM4E (0.45) | LMNAKMT2AMAPTKDM4ECYP1A2 | |
| SCHEMBL27621506 | 0.74 | MAPK1 (0.46) | LMNAALDH1A1HPGDPOLB | |
| SCHEMBL27574601 | 0.73 | KDM4E (0.44) | LMNAKMT2AMAPTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111213059-B | Diagnostic and therapeutic methods for cancer | 豪夫迈·罗氏有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111836621-A | Methods of modulating TIGIT and PD-1 signaling pathways using 1,2, 4-oxadiazole compounds | 奥瑞基尼探索技术有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-105237483-B | A kind of symmetric form pyrimidine radicals salt compounded of iodine and preparation method thereof | 东华大学 | 2018-04-20 | — | — | CN | disclosed |
| CN-105237483-A | Symmetric pyrimidyl iodonium salt and preparation method thereof | NAT UNIV DONG HWA | 2016-01-13 | — | — | CN | disclosed |