Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11774151 | 0.78 | MAPT (0.56) | MEN1KMT2AHIF1AMAPTSMN1; SMN2 | |
| SCHEMBL28075095 | 0.74 | MAPT (0.36) | MEN1KMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL20813242 | 0.70 | MAPT (0.50) | MEN1KMT2AMAPTSMN1; SMN2FFAR1 | |
| SCHEMBL6393653 | 0.68 | NR4A2 (0.46) | CA1CA2ATMMAPTGAA | |
| SCHEMBL1179448 | 0.68 | EGFR (0.59) | CA1CA2HIF1ASMN1; SMN2AKR1C3 | |
| SCHEMBL28516843 | 0.68 | GAA (0.60) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL169696 | 0.68 | MAPT (0.72) | CA1CA2MEN1KMT2AHIF1A | |
| SCHEMBL12488919 | 0.68 | NR4A2 (0.49) | CA1CA2ATMMAPTGAA | |
| SCHEMBL8345852 | 0.68 | MAPT (0.72) | CA1CA2MEN1KMT2AHIF1A | |
| SCHEMBL27523872 | 0.67 | KMT2A (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315283-A | Bruton tyrosine kinases inhibitor | CHENGDU BEISIKAIRUI BIOTECHNOLOGY CO LTD | 2016-02-10 | — | — | CN | disclosed |