Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TAS2R46 | P59540 | 12/20 | 0.37 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.37 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35483 | 0.93 | — | — | |
| SCHEMBL31545103 | 0.93 | — | — | |
| SCHEMBL6586714 | 0.79 | — | — | |
| SCHEMBL6592766 | 0.77 | LMNA (0.39) | LMNATAS2R46TAS2R31TAS2R10KMT2A | |
| SCHEMBL8677735 | 0.77 | LMNA (0.39) | LMNATAS2R46TAS2R31TAS2R10KMT2A | |
| SCHEMBL11334856 | 0.76 | KMT2A (0.40) | LMNATAS2R46TAS2R31TAS2R10KMT2A | |
| SCHEMBL31253195 | 0.71 | — | — | |
| SCHEMBL9934031 | 0.71 | — | — | |
| SCHEMBL6592171 | 0.71 | — | — | |
| SCHEMBL6588978 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858916-B | The benzotropolone and/or the relevant benzotropolone derivatives that contain plant extracts by use are stablized family expenses, watch box and food product | BASF SE (DE) | 2016-05-11 | — | — | CN | disclosed |