SCHEMBL28047965

SCHEMBL28047965

Cc1c(C)c(C)c(C(=O)c2ccccc2O)c(O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIG1 P18858 1/20 0.47
SPR P35270 1/20 0.46
KDM4E B2RXH2 8/20 0.45
HPGD P15428 7/20 0.45
ALDH1A1 P00352 7/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HMGB1 P09429 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
CA14 Q9ULX7 1/20 0.45
LMNA P02545 6/20 0.44
TSHR P16473 3/20 0.44
HSD17B10 Q99714 4/20 0.44
MAPT P10636 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10768136 0.84 LIG1 (0.46) LIG1SPRKDM4EHPGDALDH1A1
SCHEMBL27514040 0.79 ALDH1A1 (0.52) KDM4EHPGDALDH1A1LMNAHSD17B10
SCHEMBL1063410 0.78 LIG1 (0.55) LIG1SPRKDM4EHPGDALDH1A1
SCHEMBL8861227 0.76 LIG1 (0.57) LIG1SPRKDM4EHPGDALDH1A1
SCHEMBL10766603 0.75 HPGD (0.53) LIG1SPRKDM4EHPGDALDH1A1
2,2'-Dihydroxybenzphenone SCHEMBL29572496 0.75 HPGD (0.67) LIG1SPRKDM4EHPGDALDH1A1
2,2'-Dihydroxybenzphenone SCHEMBL18422 0.75 HPGD (0.67) LIG1SPRKDM4EHPGDALDH1A1
SCHEMBL27795680 0.75 LIG1 (0.52) LIG1SPRKDM4EHPGDALDH1A1
SCHEMBL9468114 0.75 LIG1 (0.52) LIG1SPRKDM4EHPGDALDH1A1
2,2'-Dihydroxybenzphenone SCHEMBL11145317 0.73 LIG1 (0.64) LIG1SPRKDM4EHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-204962165-U Novel multiple protection water pipe XU SHIGUI 2016-01-13 CN disclosed