⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726340 | 0.75 | — | — | |
| SCHEMBL9930262 | 0.73 | — | — | |
| SCHEMBL1425908 | 0.73 | — | — | |
| SCHEMBL1057489 | 0.73 | — | — | |
| SCHEMBL4963397 | 0.73 | — | — | |
| SCHEMBL10702351 | 0.73 | — | — | |
| SCHEMBL10822584 | 0.73 | — | — | |
| SCHEMBL9383004 | 0.73 | — | — | |
| SCHEMBL164274 | 0.73 | — | — | |
| SCHEMBL270744 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311870-A | estrogen receptor modulators | 芝诺罗耶尔蒂里程碑有限责任公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109311870-A | estrogen receptor modulators | 芝诺罗耶尔蒂里程碑有限责任公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-109311876-A | heteroaryl estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-108602776-A | Heteroaryl compound and application thereof as IRAK inhibitor | 默克专利有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108290879-A | Heteroaryl compound and application thereof as IRAK inhibitor | 默克专利有限公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-105229004-B | Chemical compounds | 阿斯利康(瑞典)有限公司 | 2017-05-03 | — | — | CN | disclosed |
| CN-105229004-A | Compound | ASTRAZENECA AB | 2016-01-06 | — | — | CN | disclosed |