Acetone

Acetone

SCHEMBL28048045

CC(C)=O.O=C=NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.30

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8740598 0.87 ALDH1A1 (0.32) ALDH1A1TP53TSHR
Methylene Chloride SCHEMBL27751023 0.85 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL6893027 0.81
SCHEMBL14216993 0.72
SCHEMBL22220175 0.69
Trichloroethane SCHEMBL29222125 0.69 TSHR (0.33) TSHR
SCHEMBL3822372 0.69
SCHEMBL11657364 0.69
SCHEMBL28862620 0.67 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL12329853 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112755067-A Cefuroxime axetil bulk drug 苏州盛达药业有限公司 2021-05-07 CN claimed
CN-105131016-A Preparation method of cefuroxime axetil JIANGSU CHIATAI QINGJIANG PHARMACEUTICAL CO LTD 2015-12-09 CN claimed
CN-112755067-A Cefuroxime axetil bulk drug 苏州盛达药业有限公司 2021-05-07 CN disclosed
CN-112755067-A Cefuroxime axetil bulk drug 苏州盛达药业有限公司 2021-05-07 CN disclosed