Terephthalamide

Terephthalamide

SCHEMBL28048050

N#Cc1cc(N)ccc1N.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 4/20 0.44
PARP15 Q460N3 3/20 0.44
PARP2 Q9UGN5 2/20 0.44
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 3/20 0.42
USP2 O75604 2/20 0.42
MYC P01106 1/20 0.42
LMNA P02545 1/20 0.40
CHUK O15111 1/20 0.40
MAPT P10636 3/20 0.38
HPGD P15428 2/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
TSHR P16473 1/20 0.38
POLB P06746 1/20 0.38
THRB P10828 1/20 0.38
PKM P14618 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6816025 0.87 PARP15 (0.43) PARP10PARP15PARP2KDM4EALDH1A1
SCHEMBL5305433 0.85 MYC (0.55) PARP10PARP15PARP2MYCCHUK
SCHEMBL615129 0.83 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL29802150 0.83 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT
Hydrochloric Acid SCHEMBL8435619 0.81 KDM4E (0.53) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL5070972 0.78 MAPK1 (0.43) ALDH1A1USP2LMNAMAPTTSHR
SCHEMBL4026182 0.77 CDC25B (0.50) KDM4EALDH1A1LMNAMAPTHPGD
SCHEMBL15938751 0.77 PARP15 (0.43) PARP10PARP15PARP2KDM4EALDH1A1
SCHEMBL6814562 0.77 KDM4E (0.46) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL23302174 0.75 TSHR (0.38) ALDH1A1MAPTHPGDKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105229053-B Highly functional polyamide polymer, spinning dope composition containing same, and molded product thereof 友情化学株式会社 2017-05-10 CN disclosed
CN-105229053-A High-performance poly amide polymer, the spinning coating composition comprising it and products formed thereof SK GLOBAL CHEMICAL CO LTD 2016-01-06 CN disclosed