SCHEMBL615129

SCHEMBL615129

N#Cc1cc(N)ccc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.55
ALDH1A1 P00352 5/20 0.55
USP2 O75604 2/20 0.55
LMNA P02545 2/20 0.52
MAPT P10636 5/20 0.48
HPGD P15428 4/20 0.48
CYP3A4 P08684 5/20 0.46
CYP1A2 P05177 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
CYP2C19 P33261 2/20 0.46
CYP2D6 P10635 1/20 0.46
TSHR P16473 2/20 0.41
MAPK1 P28482 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
MDM4 O15151 1/20 0.41
GAA P10253 3/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802150 1.00 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT
Hydrochloric Acid SCHEMBL8435619 0.98 KDM4E (0.53) KDM4EALDH1A1USP2LMNAMAPT
Terephthalamide SCHEMBL28048050 0.83 PARP10 (0.44) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL31037588 0.82 CYP3A4 (0.46) KDM4EALDH1A1USP2LMNACYP3A4
SCHEMBL204121 0.82 KDM4E (0.69) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL30839883 0.82 KDM4E (0.69) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL2638947 0.80 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL5072719 0.80 TDP1 (0.48) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL30799696 0.80 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT
SCHEMBL2028221 0.80 KDM4E (0.55) KDM4EALDH1A1USP2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117699788-A Graphene aerogel and preparation method and application thereof 西南科技大学 2024-03-15 CN claimed
CN-117101558-B Preparation method and application of covalent organic framework aerogel 烟台大学 2024-01-05 CN claimed
CN-117180935-A Cyano crosslinked plasticizing-resistant gas separation membrane and preparation method and application thereof 北京瑞实气体分离技术有限公司 2023-12-08 CN claimed
CN-117101558-A Preparation method and application of covalent organic framework aerogel 烟台大学 2023-11-24 CN claimed
CN-113668089-B Preparation method of aromatic polyamide membranous fibrid 中蓝晨光化工有限公司 2023-07-28 CN claimed
CN-115624922-B Amidoxime functionalized covalent organic framework and graphene oxide hybrid aerogel as well as preparation method and application thereof 烟台大学 2023-05-26 CN claimed
CN-115624922-A Amidoxime functionalized covalent organic framework and graphene oxide hybrid aerogel, and preparation method and application thereof 烟台大学 2023-01-20 CN claimed
CN-114805804-A Branched cross-linked polyamic acid solution, polyimide adhesive, and preparation method and application thereof 北京宇程科技有限公司 2022-07-29 CN claimed
CN-113668089-A Preparation method of aromatic polyamide film-shaped fibrid 中蓝晨光化工有限公司 2021-11-19 CN claimed
CN-107675283-B High-strength aromatic copolyamide fiber and preparation method thereof 崔松 2020-07-17 CN claimed
CN-107675283-A High-strength aromatic coplyamide fibre and preparation method thereof 崔松 2018-02-09 CN claimed
US-20170241048-A1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR KOLON INDUSTRIES, INC. (KR) 2017-08-24 US claimed
EP-3184675-A1 HIGH-STRENGTH COPOLYMERIZED ARAMID FIBER AND PREPARING METHOD THEREFOR Kolon Industries, Inc. (KR) 2017-06-28 EP claimed
EP-3091107-A1 COPOLYMERIZED ARAMID DOPE-DYED YARN AND METHOD FOR PREPARING SAME Kolon Industries, Inc. (KR) 2016-11-09 EP claimed
CN-104927072-A Solvent-resistant polyimide thin film with low thermal expansion coefficient and preparation method for polyimide thin film LU AN CITY DUERBANG INSULATION MATERIALS CO LTD 2015-09-23 CN claimed
CN-102364397-B Radiation-sensitive resin composition, cured film, method for forming cured film, and display device JSR CORP 2015-04-01 CN claimed
CN-101898135-A Amorphous catalyst for catalytic hydrogenation of 2-cyan-4-nitroaniline and preparation method of 2,5-diamincyanophenyl WUHAN CHEMAX CHEMICAL IND CO LTD 2010-12-01 CN claimed
CN-1212694-A Pyrimido [5,4-D] pyrimidines, medicaments containing these compounds, their use and process for their production THOMAE GMBH DR K (DE) 1999-03-31 CN claimed
US-5865856-A MIXTURE CONTAINING COUPLER AND DEVELOPER WELLA AKTIENGESELLSCHAFT (DE) 1999-02-02 US claimed
EP-0797980-A1 Oxidation hair dye composition comprising a 2,5-diaminobenzonitrile as well as 2,5-diaminobenzonitrile compounds Wella Aktiengesellschaft (DE) 1997-10-01 EP claimed