Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.73 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | SRC | P12931 | 10/20 | 0.57 |
| ▸ | ABL1 | P00519 | 3/20 | 0.57 |
| ▸ | HCK | P08631 | 1/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784908 | 0.89 | SRC (0.59) | PIK3CAHTR2CSRCABL1HCK | |
| SCHEMBL13944347 | 0.85 | PIK3CA (1.00) | PIK3CAHTR2CSRCHTR2A | |
| SCHEMBL2810687 | 0.80 | PIK3CA (0.54) | PIK3CAHTR2CSRCABL1ALDH1A1 | |
| SCHEMBL2807943 | 0.79 | SRC (0.68) | PIK3CAHTR2CSRCABL1HCK | |
| SCHEMBL2788589 | 0.79 | SRC (0.68) | PIK3CAHTR2CSRCABL1HCK | |
| SCHEMBL13943299 | 0.79 | HTR2C (0.88) | PIK3CAHTR2CHTR2A | |
| SCHEMBL13944746 | 0.79 | HTR2C (0.77) | PIK3CAHTR2CHTR2A | |
| SCHEMBL2871542 | 0.76 | PDE5A (0.51) | HTR2CSRCABL1ALDH1A1HSD17B10 | |
| SCHEMBL13944361 | 0.76 | PIK3CA (1.00) | PIK3CAHTR2CHTR2A | |
| SCHEMBL3757023 | 0.76 | HTR2C (1.00) | PIK3CAHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |