Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.68 |
| ▸ | HCK | P08631 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 6/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788589 | 0.89 | SRC (0.68) | SRCHCKPIM1PIK3CAABL1 | |
| SCHEMBL2807570 | 0.88 | PIK3CA (0.56) | SRCPIK3CAABL1HTR2CRAB9A | |
| SCHEMBL17726036 | 0.81 | SRC (1.00) | SRCHCKPIM1ABL1 | |
| SCHEMBL2784908 | 0.81 | SRC (0.59) | SRCHCKPIM1PIK3CAABL1 | |
| SCHEMBL2807509 | 0.80 | SRC (0.54) | SRCHCKPIM1PIK3CAHTR2C | |
| SCHEMBL2804830 | 0.79 | PIK3CA (0.73) | SRCHCKPIM1PIK3CAABL1 | |
| SCHEMBL2875828 | 0.77 | SRC (0.52) | SRCABL1HTR2CUSP2RAB9A | |
| SCHEMBL2810687 | 0.76 | PIK3CA (0.54) | SRCPIK3CAABL1HTR2CUSP2 | |
| SCHEMBL2788332 | 0.76 | PIK3CA (0.55) | SRCPIK3CAABL1HTR2C | |
| SCHEMBL2811187 | 0.73 | PDE2A (0.48) | SRCABL1USP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |