Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 1/20 | 0.75 |
| ▸ | CHKA | P35790 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.62 |
| ▸ | HRH2 | P25021 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045927 | 1.00 | PTGIR (0.75) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| SCHEMBL1043090 | 0.98 | SIGMAR1 (0.77) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL23850638 | 0.98 | PTGIR (0.73) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| SCHEMBL1045386 | 0.98 | SIGMAR1 (0.77) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| SCHEMBL3171551 | 0.96 | PTGIR (0.81) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| SCHEMBL1890751 | 0.94 | PTGIR (0.78) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| Hydrochloric Acid SCHEMBL518538 | 0.92 | PTGIR (0.76) | PTGIRCHKASIGMAR1SMN1; SMN2HRH3 | |
| SCHEMBL19285228 | 0.92 | SIGMAR1 (0.85) | PTGIRCHKASIGMAR1SMN1; SMN2POLB | |
| SCHEMBL20804352 | 0.92 | SIGMAR1 (0.85) | PTGIRCHKASIGMAR1SMN1; SMN2POLB | |
| SCHEMBL1043952 | 0.92 | SIGMAR1 (0.85) | PTGIRCHKASIGMAR1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367576-A | Pyrrolopyrimidine compounds as TLR7 agonists | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD | 2016-03-02 | — | — | CN | disclosed |