SCHEMBL28048566

SCHEMBL28048566

OCCCNCCNC1CCC1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 12/20 0.41
CXCL12 P48061 1/20 0.41
EPHX1 P07099 1/20 0.36
DPP4 P27487 3/20 0.35
RAD52 P43351 1/20 0.34
FAP Q12884 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28048565 0.94 CXCR4 (0.47) CXCR4CXCL12EPHX1RAD52KDM4E
SCHEMBL9949345 0.87
SCHEMBL20395033 0.83 KDM4E (0.40) CXCR4CXCL12EPHX1DPP4RAD52
SCHEMBL3541152 0.82 CXCR4 (0.46) CXCR4CXCL12EPHX1RAD52KDM4E
SCHEMBL1548264 0.80 CXCR4 (0.49) CXCR4CXCL12EPHX1RAD52KDM4E
SCHEMBL3537998 0.80 CXCR4 (0.49) CXCR4CXCL12EPHX1RAD52KDM4E
SCHEMBL9950204 0.80 CXCR4 (0.49) CXCR4CXCL12EPHX1RAD52KDM4E
SCHEMBL9950170 0.80 EPHX1 (0.47) CXCR4CXCL12EPHX1KDM4E
SCHEMBL11519285 0.79 RAD52 (0.47) CXCR4CXCL12RAD52KDM4E
SCHEMBL11522705 0.79 RAD52 (0.47) CXCR4CXCL12RAD52KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103505994-B Acid gas absorbent, sour gas minimizing technology and sour gas removal device TOSHIBA CORP (JP) 2015-12-09 CN disclosed