Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945951 | 0.86 | POLB (0.51) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL28048643 | 0.86 | POLB (0.46) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27933632 | 0.85 | POLB (0.53) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL28162947 | 0.80 | PDE4B (0.47) | ALDH1A1TSHRMEN1KMT2APPARA | |
| SCHEMBL28013053 | 0.79 | MEN1 (0.43) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL25139472 | 0.79 | KCNQ3 (0.50) | ALDH1A1TSHRMEN1KMT2APDE4B | |
| SCHEMBL661011 | 0.79 | PDE4B (0.62) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL25139577 | 0.79 | MEN1 (0.62) | ALDH1A1TSHRPOLBMEN1KMT2A | |
| SCHEMBL27553770 | 0.78 | MEN1 (0.48) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL27319416 | 0.77 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814024-B | Aromatic compounds and application thereof | 住友化学株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-105263921-B | Terazololine-one compound and its application | 住友化学株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-106660991-A | Antiproliferative compounds and methods of use thereof | 细胞基因公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-105814024-A | Aromatic compound and application for same | 住友化学株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-105263921-A | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL CO | 2016-01-20 | — | — | CN | disclosed |