Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048633 | 0.86 | ALDH1A1 (0.50) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL27945951 | 0.84 | POLB (0.51) | POLBALDH1A1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL27933632 | 0.82 | POLB (0.53) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL28016532 | 0.81 | PDE4B (0.45) | POLBALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL28016861 | 0.76 | NPC1 (0.51) | HDAC1HDAC8HDAC6HPGDFFAR4 | |
| SCHEMBL16370064 | 0.74 | KMT2A (0.49) | POLBALDH1A1TSHRKMT2ACSNK2A1 | |
| SCHEMBL12227520 | 0.72 | RORC (0.48) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2589062 | 0.72 | ALDH1A1 (0.50) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL12697235 | 0.71 | NOS3 (0.50) | POLBALDH1A1TSHRMAPTNOS3 | |
| SCHEMBL2772853 | 0.70 | ALDH1A1 (0.48) | POLBALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105263921-B | Terazololine-one compound and its application | 住友化学株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-105263921-A | Tetrazolinone compound and application of same | SUMITOMO CHEMICAL CO | 2016-01-20 | — | — | CN | disclosed |